Vladimir Agabekov, Director, Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, Doctor of Chemical Sciences;
Viktoryia Kulikouskaya, Head of laboratory, Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, Candidate of Chemical Sciences;
Kseniya Hileuskaya, senior researcher, Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, Candidate of Chemical Sciences;
Katsiaryna Dubatouka, junior researcher, post-graduate student, Institute of Chemistry of New Materials, National Academy of Sciences of Belarus.
Summary.
The article considers the natural polymers (polysaccharides, proteins) and lipids based carriers for biologically active substances providing targeted delivery and/or prolonged release. There have been obtained the multilayer microcapsules and hydrogel nanoparticles containing imatinib methanesulfonate and providing increase in its cytotoxic effect as compared to the native form, and liposomal form of streptokinase with prolonged thrombolytic effect.
Key words: microcapsules, nanoparticles, liposomes, biopolymers, biologically active compounds, prolonged action, target delivery.
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