
Elizaveta Bon, associate professor of the Department of Pathological Physiology, Grodno State Medical University, Candidate of Biological Sciences;
Natalia Maksimovich, Head of the Department of Pathological Physiology, Grodno State Medical University, Doctor of Biological Sciences, professor;
Iosif Dremza, associate professor of the Department of Pathological Physiology, Grodno State Medical University, Candidate of Biological Sciences;
Olga Karnyushko, associate professor of the Department of Histology, Cytology and Embryology, Grodno State Medical University, Candidate of Biological Sciences;
Sergei Zimatkin, Head, Department of Histology, Cytology and Embryology, Grodno State Medical University, Doctor of Biological Sciences, professor;
Alexandra Koiko, 3rd year student of the Faculty of Pediatrics, Grodno State Medical University;
Violetta Shevchuk, 3rd year student of the Faculty of Pediatrics, Grodno State Medical University;
Maria Lychkovskaya, 4th year student of the Faculty of Pediatrics, Grodno State Medical University.
Summary.
The authors studied the parameters of mitochondria respiration of brain homogenates and the content of ATP synthase in rats with cerebral ischemia and under conditions of administration of ?-3 polyunsaturated fatty acids, which have an anti-inflammatory effect, regulate vascular tone and prevent vascular vasoconstriction under the influence of catecholamines. There was observed their beneficial effect on the structures of the hippocampus in subtotal cerebral ischemia and lesser severity of manifestations of neurological deficit, as compared with the group without their administration.
Key words: ATP synthase, neurons, cerebral ischemia, mitochondria, ?-3 polyunsaturated fatty acids, ADP.
References.
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